31 Quotes by David Andrew Sinclair

I thought that tackling aging and the mechanisms that promote life would be worth figuring out. I wanted to learn why it is that some people are healthier than others and why some people live to 110 and others only to 60 or 70.

It's been known since 1916 that cutting back calories is beneficial in every organism it's been tested on - from yeast to worms to mice to monkeys. I think it would be a surprise if we are an exception to that rule.

As we get better at reversing aging it will be possible to take one medicine and within weeks feel and even look younger. Imagine going to a doctor to get a pill for diabetes, and this same medicine will prevent heart disease, Alzheimer's, cancer, and will give you more vitality too.

The ultimate goal is to have a pill that can prevent or reverse all diseases of aging. The major diseases that I'd like to tackle are heart disease, diabetes, Alzheimer's and cancer. I want to reduce those diseases by 10 percent.

I actually think it will be possible one day to be immortal.

I was criticized for saying that Pfizer doesn't know how to make a molecule right.

Well, we can study aging in people, but of course those studies take decades. So what we try to do is we use simpler organisms to try and understand the basic mechanisms and so in my laboratory, for example, we use things like simple baker's yeast that we use to make bread.

We used to think that aging was a lot like, as if we were cars made fresh and youthful and then we've entered this breakdown in diet. What we didn't realize until recently is that we're much more complex than a car. We fix ourselves if we're broken.

Well, originally we found resveratrol just in a test tube, looking for molecules that would turn on this enzyme, this protein that seems to defend against diseases in aging.