156 Quotes by Francis Collins

[The tests agreed] that I was at higher risk than the average person for Type 2 diabetes, which is what my lab works on. In fact, some of the things they were testing for were variants that we had discovered.

A lot of science doesn't require big "ns" but if you're trying to understand something about human health and you're looking at interventions that are not going to be either killing you or making you live forever - they're going to have some tweaking on the outcome - you need big numbers or you don't have enough power.

What wakes me up at night is this next generation and what's happening to them. And they're invariably excited about the science that they're doing, but invariably anxious about where there's a future.

I'm a serious Christian. I take my faith seriously.

The blooming of a flower is, in my mind, not a miracle. It's something that we can understand on the basis of molecular biology these days

What does it take to get people interested, what does it take to get people engaged, what does it take to get them to give a biospecimen? What does it take to get people like Jim [Ostell] to get interested and engaged, versus someone like my mother?

A lot of people think PMI is the genome project 2.0. No. This is about all the influences on disease - genetics is in there, but the environment is in there as well, health choices, behaviors, all the factors that are important, otherwise we're not doing what we promised we would do - which is in a holistic way look at how people stay healthy or how do they fall ill.

It's not like you're closing the old doors and that investigators working away in a laboratories on a unique hypothesis are no longer needed. My gosh, they are indeed. But this becomes a real engine for hypothesis generation and even for proof if you have interventions that you can carry out in this kind of large scale and conduct them in a rigorous way. I guess, yeah, it's different. But it's different in a good way.

I had the analysis of a million or so SNPs [single nucleotide polymorphisms] just to see what was there. That's partly because I was writing a book about DNA and personalized medicine and I thought it would be a little bit disingenuous to talk about what could be done without actually having the experiment done on yourself.