I have a reverence for medicine because I hero-worshiped my father [a former doctor], and because I admire doctors, I admire study, empiricism and rational thought. I don't study, empiricize or think rationally myself - but I admire it in others.

I think good-looking people seldom make good television. And American television studios almost concede before they start: 'Well, it won't be good, but at least it'll be good-looking. We'll have nice-looking girls in tight shirts with F.B.I. badges and fit-looking guys with lots of hair gel vaulting over things.'

Success on a cosmic level completely eludes me. I'm deeply suspicious of things being too good. It's part of my superstition, I think, to generate pain in order to give the illusion of gain. I'm not saying I reject success, but honestly, I don't quite know how to deal with it. It's an old feeling: As soon as you have the thing you've been going after all your life, that reasonable degree of security, you start kicking against it, doubting it.

I never went to drama school, I don't have any certificates saying: 'He's a qualified actor.' But I did think that 'House' was something I didn't have to apologise for. It was something I was really proud of and it was sort of... whether you liked it or not, it was undeniable.

I don't talk like House, or walk like him. I certainly don't think like him. I don't like to think for more than 15 minutes at a stretch actually; I am a fragile flower.

Boxing is fascinating. It's good for the soul to be made to feel clumsy. I swank around during the week thinking I'm a big cheese, but you don't feel like that when you're in the ring with a chap who knows what he's doing. It's ritual humiliation. I'm going to be slugged about and probably killed, but I love it and have to do something to keep fit.

I would just hear piano players and I would hear music, and just think - I don't just want to sit here and passively listen; I want to get inside it.

Believe it or not, perhaps I don't show it much, or well, but I think I like people.

I know a lot of people think therapy is about sitting around staring at your own navel - but it's staring at your own navel with a goal. And the goal is to one day to see the world in a better way and treat your loved ones with more kindness and have more to give.