[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$fTEqvvDj9T6T9kOgOwK6sZOvAv5UsQKRidwBzDtPE1NA":3,"$fAWDoBBTjTy9pyam2rauaskDU9Kg_GcBsHVC17Aa1fsI":12},{"author":4,"tags":11},{"author_id":5,"author_name":6,"author_name_first_letter":7,"article_count":8,"bio":9,"short_bio":9,"bio_jsonld":9,"slug":10,"image_url":9},172743,"Gregory Petsko","G",9,null,"gregory-petsko",[],{"quotes":13,"pagination":108},[14,22,34,45,56,69,80,91,102],{"id":15,"quote_text":16,"author_id":5,"source_id":17,"has_image":18,"author":19,"source":20,"quote_tag":21,"commentary":9},2210720,"A whole host of things that we now know are drugs turn out to be plant alkaloids.",4,false,{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[],{"id":23,"quote_text":24,"author_id":5,"source_id":17,"has_image":18,"author":25,"source":26,"quote_tag":27,"commentary":33},2210707,"Synchrotron light has revolutionized the field of protein crystallography. It has made it possible to look at much larger structures with much smaller crystals.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[28],{"id":29,"tag":30},5194901,{"id":31,"tag_name":32},10364,"larger","**The Backstory**\nGregory Petsko, a renowned biochemist, made this statement in the context of his groundbreaking work in protein crystallography. At the time, he was actively contributing to the field's rapid progress, leveraging cutting-edge technology to decipher the structures of proteins. The quote reflects his enthusiasm for the synchrotron light source, a novel tool that significantly expanded the scope of his research.\n\n**The Hidden Insight**\nWhile the quote may seem like a straightforward celebration of technological advancements, it reveals a deeper tension between the desire for resolution and the reality of complexity. Petsko's statement highlights the paradox that, as we gain the ability to examine larger structures, we may inadvertently overlook the intricate details that make these systems function.\n\n**How to Use This**\nIn modern professional and creative endeavors, this insight can be applied by recognizing that progress often requires embracing the paradox of increasing complexity. Instead of seeking to simplify complex systems, modern professionals can leverage advanced tools and technologies to reveal the intricate details that underlie their work, fostering a deeper understanding of the challenges they face.",{"id":35,"quote_text":36,"author_id":5,"source_id":17,"has_image":18,"author":37,"source":38,"quote_tag":39,"commentary":9},2210702,"Almost without exception, the talented women I have known have believed they had less ability than they actually had. And almost without exception, the talented men I have known believed they had more.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[40],{"id":41,"tag":42},5194893,{"id":43,"tag_name":44},24218,"almost",{"id":46,"quote_text":47,"author_id":5,"source_id":17,"has_image":18,"author":48,"source":49,"quote_tag":50,"commentary":9},2210698,"I think the decision to make substances like steroids from plants, rather than from animal tissues, was a landmark in the history of medicine as well as the history of chemistry.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[51],{"id":52,"tag":53},5194889,{"id":54,"tag_name":55},462,"history",{"id":57,"quote_text":58,"author_id":5,"source_id":17,"has_image":59,"author":60,"source":61,"quote_tag":62,"commentary":68},2210686,"Synthesis is the process of making a natural product, or some other substance, artificially, in the lab, one step at a time, from extremely simple building blocks.",true,{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[63],{"id":64,"tag":65},5194881,{"id":66,"tag_name":67},8128,"building","**The Backstory**\n\nGregory Petsko, a renowned biochemist and Nobel laureate, likely spoke these words in his lectures or interviews, perhaps during a period when he was refining the concept of protein synthesis. The era of molecular biology was burgeoning, and scientists like Petsko were pushing the boundaries of understanding how living organisms build complex structures from simple components.\n\n**The Hidden Insight**\n\nAt first glance, the quote seems to be a straightforward description of laboratory techniques. However, it belies a profound philosophical truth: that creation is not solely an act of divine inspiration or natural occurrence but also a process that can be understood and replicated through systematic, incremental steps. The emphasis on \"extremely simple building blocks\" reveals a fundamental aspect of scientific inquiry – the recognition that even the most complex phenomena arise from basic components.\n\n**How to Use This**\n\nWhen tackling a challenging project or innovation, adopt Petsko's mindset by breaking down the problem into its constituent parts and focusing on the smallest, most manageable steps. By doing so, you'll not only make steady progress but also appreciate the beauty of how seemingly disparate elements can coalesce into something remarkable through the power of incremental synthesis.",{"id":70,"quote_text":71,"author_id":5,"source_id":17,"has_image":18,"author":72,"source":73,"quote_tag":74,"commentary":9},2210675,"If you want to lower your risk of Parkinson's disease, caffeine is protective to some extent; nobody knows why. Head injuries are bad for you. They lead to Parkinson's disease.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[75],{"id":76,"tag":77},5194868,{"id":78,"tag_name":79},2891,"bad",{"id":81,"quote_text":82,"author_id":5,"source_id":17,"has_image":18,"author":83,"source":84,"quote_tag":85,"commentary":9},2210667,"As far as protecting yourself against Alzheimer's disease, well, it turns out that fish oil has the effect of reducing your risk for Alzheimer's disease. You should also keep your blood pressure down, because chronic high blood pressure is the biggest single risk factor for Alzheimer's disease.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[86],{"id":87,"tag":88},5194856,{"id":89,"tag_name":90},1486,"against",{"id":92,"quote_text":93,"author_id":5,"source_id":17,"has_image":18,"author":94,"source":95,"quote_tag":96,"commentary":9},2210646,"For thousands of years, long before there was such a thing as a science of chemistry, people were fascinated by plants, because they knew that plants contained substances that could affect people. Coffee will keep you awake. Tobacco contains something that will calm your nerves. Foxglove contains an extract that'll affect your heart.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[97],{"id":98,"tag":99},5194839,{"id":100,"tag_name":101},10690,"affect",{"id":103,"quote_text":104,"author_id":5,"source_id":17,"has_image":18,"author":105,"source":106,"quote_tag":107,"commentary":9},2210631,"Alzheimer's disease starts when a protein that should be folded up properly misfolds into a kind of demented origami.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[],{"currentPage":109,"totalPages":109,"totalItems":8,"itemsPerPage":110},1,10]