[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$f3O7908-U6CsS6EnVw0jVELED6PCcDDsVWRTmV3bXzSI":3,"$flm2WDPmCtCKukb2NlcyC8SfV_9d8IwCSXBr-tGG5hF0":12},{"author":4,"tags":11},{"author_id":5,"author_name":6,"author_name_first_letter":7,"article_count":8,"bio":9,"short_bio":9,"slug":10,"image_url":9},162902,"Henry Markram","H",16,null,"henry-markram",[],{"quotes":13,"pagination":113},[14,22,28,40,51,57,69,80,91,102],{"id":15,"quote_text":16,"author_id":5,"source_id":17,"has_image":18,"author":19,"source":20,"quote_tag":21,"commentary":9},3694974,"People are afraid of detail and complexity.",7,false,{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[],{"id":23,"quote_text":24,"author_id":5,"source_id":17,"has_image":18,"author":25,"source":26,"quote_tag":27,"commentary":9},3694939,"99 percent of what you see is not what comes in through the eyes. It is what you infer about that room.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[],{"id":29,"quote_text":30,"author_id":5,"source_id":31,"has_image":18,"author":32,"source":33,"quote_tag":34,"commentary":9},2013875,"We cannot experimentally map out the brain. Its just too big. In a piece of the brain the size of a pinhead there are 3,000 pathways like a city with 3,000 streets.",4,{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[35],{"id":36,"tag":37},5001170,{"id":38,"tag_name":39},12307,"cities",{"id":41,"quote_text":42,"author_id":5,"source_id":31,"has_image":18,"author":43,"source":44,"quote_tag":45,"commentary":9},2013863,"Think of a forest, then imagine taking 10,000 trees and squeezing them together until there is essentially no space between them. That's what the neocortical column looks like.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[46],{"id":47,"tag":48},5001158,{"id":49,"tag_name":50},291463,"column",{"id":52,"quote_text":53,"author_id":5,"source_id":31,"has_image":18,"author":54,"source":55,"quote_tag":56,"commentary":9},2013855,"There are few scientists in the world with the resources I have at my disposal.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[],{"id":58,"quote_text":59,"author_id":5,"source_id":31,"has_image":18,"author":60,"source":61,"quote_tag":62,"commentary":68},2013843,"The best way to figure out how something works is to try to build it from scratch.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[63],{"id":64,"tag":65},5001138,{"id":66,"tag_name":67},2294,"best","**The Backstory**\n\nThis quote is attributed to Henry Markram, a neuroscientist and the founding director of the Blue Brain Project at EPFL in Switzerland. As a researcher, he was known for his ambitious goal of reverse-engineering the human brain by building a digital replica from scratch. During this time (late 2000s), computational neuroscience was still in its infancy, and Markram's approach was revolutionary.\n\n**The Hidden Insight**\n\nWhat's often missed is that Markram's statement isn't just about figuring out how something works through hands-on experimentation; it's also about acknowledging the limitations of abstraction. The act of building from scratch forces one to confront the inherent complexity and messiness of real-world systems, which can't be fully captured by models or theories alone.\n\n**How to Use This**\n\nTo apply this mindset today, try breaking down your own complex problems into tangible, buildable components. Instead of getting bogged down in theoretical frameworks, start sketching out a rough prototype or mockup that represents the key elements at play. By doing so, you'll not only gain a deeper understanding of how the pieces fit together but also develop a more practical and iterative approach to problem-solving.",{"id":70,"quote_text":71,"author_id":5,"source_id":31,"has_image":18,"author":72,"source":73,"quote_tag":74,"commentary":9},2013828,"As scientists, we need to not be afraid of the truth.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[75],{"id":76,"tag":77},5001124,{"id":78,"tag_name":79},713,"truth",{"id":81,"quote_text":82,"author_id":5,"source_id":31,"has_image":18,"author":83,"source":84,"quote_tag":85,"commentary":9},2013819,"Drug discovery is terribly expensive, just to find out how one drug could or could not work and all its side effects.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[86],{"id":87,"tag":88},5001113,{"id":89,"tag_name":90},10708,"side",{"id":92,"quote_text":93,"author_id":5,"source_id":31,"has_image":18,"author":94,"source":95,"quote_tag":96,"commentary":9},2013808,"We cannot experimentally map out the brain. It's just too big. In a piece of the brain the size of a pinhead there are 3,000 pathways like a city with 3,000 streets.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[97],{"id":98,"tag":99},5001101,{"id":100,"tag_name":101},11378,"cannot",{"id":103,"quote_text":104,"author_id":5,"source_id":31,"has_image":18,"author":105,"source":106,"quote_tag":107,"commentary":9},2013788,"Today, you have neuroscientists working on a genetic, behavioural or cognitive level, and then you have informaticians, chemists and mathematicians. They all have their own understanding of how the brain functions and is structured. How do you get them all around the same table?",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[108],{"id":109,"tag":110},5001089,{"id":111,"tag_name":112},41950,"cognitive",{"currentPage":114,"totalPages":115,"totalItems":8,"itemsPerPage":116},1,2,10]