[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$fbTYjByqn-wkO7wI9H2jN_hCgpBl06MaeEL6gNnZnIxc":3,"$fhLLx4wc67sA96a8OSz_w7978XxrKoaA-oIV-50EvJRY":12},{"author":4,"tags":11},{"author_id":5,"author_name":6,"author_name_first_letter":7,"article_count":8,"bio":9,"short_bio":9,"slug":10,"image_url":9},151554,"Rudolf Jaenisch","R",9,null,"rudolf-jaenisch",[],{"quotes":13,"pagination":109},[14,27,38,47,58,70,76,87,98],{"id":15,"quote_text":16,"author_id":5,"source_id":17,"has_image":18,"author":19,"source":20,"quote_tag":21,"commentary":9},1780854,"This paper demonstrates clearly that it doesn't matter if a stem cell has been derived from a cloned embryo or from a fertilized embryo.",4,false,{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[22],{"id":23,"tag":24},4771647,{"id":25,"tag_name":26},20967,"cell",{"id":28,"quote_text":29,"author_id":5,"source_id":17,"has_image":18,"author":30,"source":31,"quote_tag":32,"commentary":9},1780846,"Our experiments are very clear. You inhibit this gene and you get a clone that has no way of ever implanting. But this clone can make embryonic stem cells.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[33],{"id":34,"tag":35},4771635,{"id":36,"tag_name":37},30356,"clone",{"id":39,"quote_text":40,"author_id":5,"source_id":17,"has_image":18,"author":41,"source":42,"quote_tag":43,"commentary":9},1780840,"The success of this procedure in no way precludes the need to pursue all forms of human embryonic stem cell research, ... Human embryonic stem cells are extraordinarily complicated. If we are ever to realize their therapeutic potential, we must use all known tools and techniques in order to explore the mechanisms that give these cells such startling characteristics.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[44],{"id":45,"tag":46},4771624,{"id":25,"tag_name":26},{"id":48,"quote_text":49,"author_id":5,"source_id":17,"has_image":18,"author":50,"source":51,"quote_tag":52,"commentary":9},1780815,"We do experiments with animals and we know there is a major problem, which is not solved, so one should not do this with humans because humans are not guinea pigs.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[53],{"id":54,"tag":55},4771612,{"id":56,"tag_name":57},362,"animals",{"id":59,"quote_text":60,"author_id":5,"source_id":17,"has_image":18,"author":61,"source":62,"quote_tag":63,"commentary":69},1780801,"Our work is the first proof-of-principle study to show that altered nuclear transfer not only works but is extremely efficient.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[64],{"id":65,"tag":66},4771591,{"id":67,"tag_name":68},59604,"altered","**The Backstory**\nRudolf Jaenisch, a renowned biologist, uttered these words in the early 1990s, a pivotal moment in the history of stem cell research. At that time, Jaenisch and his team were pioneering the field of nuclear transfer, a technique that allows scientists to reprogram adult cells into embryonic-like stem cells. Their groundbreaking study marked a significant breakthrough in understanding the potential of altered nuclear transfer for regenerative medicine.\n\n**The Hidden Insight**\nBeneath the surface of Jaenisch's statement lies a counter-intuitive truth: **efficiency is not necessarily a measure of success, but rather a byproduct of a well-designed experiment**. Jaenisch's emphasis on the \"proof-of-principle\" aspect of their study reveals that the true value of their work lay not in its efficiency, but in its demonstration of the underlying scientific concept.\n\n**How to Use This**\nIn your own work, focus on designing experiments that validate the underlying principles, rather than solely optimizing for efficiency. By prioritizing the proof-of-principle, you'll be able to uncover new insights and make meaningful contributions to your field, even if your initial attempts are not immediately successful.",{"id":71,"quote_text":72,"author_id":5,"source_id":17,"has_image":18,"author":73,"source":74,"quote_tag":75,"commentary":9},1780781,"It is not responsible at this stage to even consider the cloning of humans.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[],{"id":77,"quote_text":78,"author_id":5,"source_id":17,"has_image":18,"author":79,"source":80,"quote_tag":81,"commentary":9},1780761,"It is clear now that every experiment published by Hwang will have to be confirmed in some way before being believed.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[82],{"id":83,"tag":84},4771553,{"id":85,"tag_name":86},14500,"clear",{"id":88,"quote_text":89,"author_id":5,"source_id":17,"has_image":18,"author":90,"source":91,"quote_tag":92,"commentary":9},1780741,"Knowing more about the process and about the precise areas of the brain that are affected will give us options for exploring future therapies.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[93],{"id":94,"tag":95},4771533,{"id":96,"tag_name":97},86659,"affected",{"id":99,"quote_text":100,"author_id":5,"source_id":17,"has_image":18,"author":101,"source":102,"quote_tag":103,"commentary":9},1780722,"The purpose of our study was to provide a scientific basis for the ethical debate.",{"id":5,"author_name":6,"slug":10,"author_name_first_letter":7,"article_count":8,"image_url":9},{},[104],{"id":105,"tag":106},4771521,{"id":107,"tag_name":108},3583,"basis",{"currentPage":110,"totalPages":110,"totalItems":8,"itemsPerPage":111},1,10]