Ascorbic acid (vitamin C, ascorbate) has a controversial history in cancer treatment, ... Observational reports described ascorbate, given in pharmacologic doses of 10 g daily, as effective in treating some cancers and in improving patient well-being. Subsequently, the same dose had no effect on patient well-being and survival in two double-blind placebo-controlled trials, and ascorbate was discarded as a treatment modality.

-Mark Levin

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