[Europeans lived] in dense, settled populations- cities- where human & animal waste breeds vermin, like mice and rats and roaches. Most of the indigenous peoples of the Americas, though, didn't live in dense settlements, and even those who lived in villages tended to move with the seasons, taking apart their towns and rebuilding them somewhere else. They didn't accumulate filth, and they didn't live crowds. They suffered from very few infectious diseases.

-Jill Lepore

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