13 Quotes by Randolph M. Nesse

Most behavior is in pursuit of a goal. Some efforts are attempts to get something, others to escape or prevent something. Either way, an individual is usually trying to make progress toward some goal. High and low moods are aroused by situations that arise during goal pursuit. What situations? A generic but useful answer is: high and low moods were shaped to cope with propitious and unpropitious situations.

[Mood allocates] investments of time, effort, resources, and risk taking to maximize Darwinian fitness in situations of varying propitiousness. High and low moods adjust cognition and behavior to cope with propitious and unpropitious situations.

Like fever and pain, anxiety and low mood are useful normal responses to some situations.

The kinds of attention we get on social media is really very much like crack cocaine. We have social obesity I call it—we can’t stop our consumption of opportunities to display ourselves and get feedback from other people.

Why has the medical profession not taken advantage of the help available from evolutionary biology, a well-developed branch of science with great potential for providing medical insights? One reason is surely the pervasive neglect of this branch of science at all educational levels. Religious and other sorts of opposition have minimized the impact in general education of Darwin's contributions to our understanding of ourselves and the world we live in.

Chlamydia, today´s most common cause of venereal disease, does the equivalent of hiding in the police station.Schistosomes of the mansoni type go a step further and essentially steal police uniforms. These parasites, a serious cause of liver disease in Asia, pick up blood-group antigens so that they may look to the immune system like our own normal blood cells.

Darwinism gives no moral guidelines about how we should live or how doctors should practice medicine. A Darwinian perspective on medicine can, however, help us to understand the evolutionary origins of disease, and this knowledge will prove profoundly useful in achieving the legitimate goals of medicine.

Categories make for efficient communication and statistical recordkeeping. They also satisfy the human lust for making things seem simpler than they are. We have been trying to map the landscape of mental disorders by drawing lines around clusters of symptoms as if they were island, but mental disorders are more like ecosystems...defying crisp boundaries.

Natural selection involves no plan, no goal, and no direction — just genes increasing and decreasing in frequency depending on whether individuals with those genes have, relative to other individuals, greater or lesser reproductive success.